The two major protease inhibitors in human serum, alpha 1 ‐antitrypsin ( α1 AT) and alpha 2 ‐macroglobulin ( α2 m), were analysed for their effects on antibody‐dependent cell‐mediated cytotoxocity (ADCC) and natural killing (NK). The results indicate that both α1 AT and α2 m decrease ADCC and NK in a dose‐responsive pattern.
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Ades et al. (1982) studied this question.
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