Colorectal cancer (CRC) is a major cause of morbidity and mortality [ 1 , 2 ]. CRC screening by fecal occult blood testing (FOBT) has been shown to reduce CRC mortality [ 3 , 4 ], and is currently used in several European countries. Colonoscopy is highly effective for detecting advanced neoplasia, and endoscopic polypectomy reduces subsequent CRC-specific incidence and mortality [ 5 ]. In Europe, colonoscopy is mainly used to investigate FOBT-positive or symptomatic patients, or as a preventive strategy in those with increased CRC risk [ 6 ].
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Spada et al. (2014) studied this question.
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