Some cases of solar urticaria are characterized by a circulating, transferable serum factor being essential in the pathogenesis of this disease. A patient with severe solar urticaria exhibited clinically, and both by in vivo and in vitro testing, marked urticarial reactions after irradiation with visible and UVA light. Treatment by plasmapheresis led to a sudden and dramatic therapeutic effect. A significant increase of the light tolerance was demonstrated by a battery of in vivo and in vitro tests and the patient was able to spend her holidays on the beaches of southern Europe. The therapeutic effect of one plasmapheresis tasted for more than 5 months. Plasmapheresis may represent a new and powerful therapeutic facility for some patients with solar urticaria.
No takes yet. Share an insight, caveat, or question.
Duschet et al. (1987) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: