Why the study?
Does tooth brushing frequency influence the incidence of major adverse cardiovascular events in patients with coronary artery disease?
Does tooth brushing frequency influence the incidence of major adverse cardiovascular events in patients with coronary artery disease?
Insufficient tooth brushing frequency (once daily) is associated with a significantly higher risk of major adverse cardiovascular events in patients with coronary artery disease compared to brushing twice or more daily.
Coronary artery disease (CAD) is a prevalent and high-mortality condition globally. The awareness regarding adequate oral care in China was insufficient. This study investigates the outcomes of CAD patients in southwest China based on their tooth brushing frequency. A total of 841 CAD patients were selected from a cohort of 32,709 residents. Over a four-year follow-up period, the incidence of three-point major adverse cardiovascular events (3P-MACEs) was evaluated. The results indicated that the hazard ratios (HR) with 95% confidence intervals (CIs) for 3P-MACEs among the three groups of tooth brushing frequency (twice, once, and thrice daily) were: reference, 1.61 (1.09-2.37) (p = 0.017), and 0.49 (0.15-1.62) (p = 0.241). Patients who brushed their teeth only once a day had a 1.71 (1.18-2.46) times higher risk compared to those who brushed twice or more daily (p = 0.004). In conclusion, insufficient tooth brushing frequency appears to be associated with a higher risk of adverse outcomes among CAD patients.
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Qiu et al. (2025) studied this question.
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