Intubation and Mechanical Ventilation in Patients with Acute Pulmonary Embolism: A Scoping Review
Why the study?
High-risk acute pulmonary embolism may require emergency endotracheal intubation and mechanical ventilation, which are thought to exacerbate cardiorespiratory instability.
What is the incidence of peri-intubation adverse events in patients with acute pulmonary embolism undergoing intubation and mechanical ventilation?
Comparison
Intubation and positive pressure ventilation
Design
Scoping review / systematic literature review
Follow-up
Peri-intubation period
Authors
Discussion
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Member takes
Implication
Alerts clinicians to high peri-intubation collapse risk in acute PE; confirms RV dysfunction link and supports prevention trials.
Structured PICO
What is the incidence of peri-intubation adverse events in patients with acute pulmonary embolism undergoing intubation and mechanical ventilation?
P
Population
104 patients with acute pulmonary embolism (PE) pooled from 3 retrospective studies
I
Intervention
Endotracheal intubation and positive pressure mechanical ventilation
O
Outcome
Adverse events during the peri-intubation periodsafety
Endotracheal intubation in patients with acute pulmonary embolism is associated with a high risk of peri-intubation hemodynamic collapse (19-28%), highlighting the need for careful patient selection and management.
Limitations
- Current evidence is limited (only 3 retrospective studies included)
Cite This Study
Lee et al. (2024) studied this question.