Following an increase in the number of patients attending the accident and emergency department because of accidental injection of adrenaline from autoinjector devices prescribed for patients with severe allergic reactions, a review of published reports was undertaken to identify the best form of treatment. Local injection of phentolamine is effective for up to 13 hours after the inadvertent digital instillation of adrenaline.
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Sean McGovern (1997) studied this question.
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