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December 1, 2010Advances in Pulmonary HypertensionOpen Access

Health-related Quality of Life in Pulmonary Arterial Hypertension

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Population

Patients with pulmonary arterial hypertension (PAH) across 23 reviewed studies.

Design

Systematic_review

Follow-up

usually 12 to 16 weeks

Authors

AGAnn Gihl

Discussion

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Implication

HRQoL tools in PAH need disease-specific validation; leaves open optimal therapy selection pending longer trials.

Structured PICO

P
Population
Patients with pulmonary arterial hypertension (PAH) across 23 reviewed studies.
I
Intervention
Various interventions including pharmaceutical therapies (epoprostenol, iloprost, treprostinil, sildenafil, bosentan, ambrisentan, sitaxsentan), exercise training, and nursing interventions.
O
Outcome
Health-related quality of life (HRQoL)patient reported

This review highlights that while PAH severely impacts HRQoL and some therapies offer benefits, the field lacks robust, long-term data using disease-specific measurement tools like CAMPHOR.

Limitations

  • Small sample sizes
  • Differences in PAH etiology and comorbidities
  • Use of non-disease-specific HRQoL tools
  • Short study durations (usually 12-16 weeks)

Cite This Study

Ann Gihl (2010) studied this question.

synapsesocial.com/papers/6a813b33ba5888e95f4d7fd8https://doi.org/10.21693/1933-088x-8.4.215
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Also Consider

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  1. 1Psychophysical bases of perceived exertion1982 · 16,695 citations
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  3. 3Cognitive, emotional, and quality of life outcomes in patients with pulmonary arterial hypertension2006 · 116 citations
  4. 4Sitaxsentan Therapy for Pulmonary Arterial Hypertension2003 · 707 citations