Granulomatous Sarcoid Disease of the Kidney

Case Studies1 October 1964Granulomatous Sarcoid Disease of the KidneyRICHARD IAN OGILVIE, M.D., MICHAEL KAYE, M.B., B.S., F.R.C.P. (C), SEAN MOORE, M.D., D.CH.RICHARD IAN OGILVIE, M.D.Search for more papers by this author, MICHAEL KAYE, M.B., B.S., F.R.C.P. (C)Search for more papers by this author, SEAN MOORE, M.D., D.CH.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-4-711 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough it is nearly fifty years since Schaumann (1) first brought attention to systemic involvement in sarcoidosis, the etiology of this disease has yet to be established, and yearly there are new reports of its varied manifestations. The majority of cases of renal impairment in sarcoidosis are attributed to associated hypercalcemia, hypercalcuria, and nephrocalcinosis (2-4). However, in 1955 Berger and Relman (5) reported a patient with generalized sarcoidosis and renal impairment due to sarcoid infiltration without nephrocalcinosis. This paper concerns a similar patient proved to have renal involvement by sarcoid infiltration of the kidneys.CASE REPORTH. B. is a...References1. SCHAUMANN J: Benign lymphogranuloma and its cutaneous manifestations. Brit. J. Derm. 36: 515, 1924. CrossrefGoogle Scholar2. KLATSKINGORDON GM: Renal complications of sarcoidosis and their relationship to hypercalcemia. Amer. J. Med. 15: 484, 1953. CrossrefMedlineGoogle Scholar3. SCHOLTZKEATING DAFR: Renal insufficiency, renal calculi and nephrocalcinosis in sarcoidosis. Amer. J. Med. 21: 75, 1956. CrossrefMedlineGoogle Scholar4. BURRFARRELHILLS JMJJAG: Sarcoidosis and hyperparathyroidism with hypercalcemia: special usefulness of cortisone test. New Eng. J. Med. 261: 1271, 1959. CrossrefMedlineGoogle Scholar5. 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(Chicago) 57: 523, 532, 1954. MedlineGoogle Scholar12. KLINEFELTERSALLEY HFSM: Sarcoidosis simulating glomerulonephritis. Bull. Hopkins Hosp. 79: 333, 1946. MedlineGoogle Scholar13. CHANIAL G (quoted in Ref. 14): Etiologie du Syndrome de Besner-Boeck. Thèse de Lyon, 1937. Google Scholar14. RUTISHAUSERRYWLIN EA: Besner-Boeck rénal. J. d'Urol. (Paris) 56: 277, 1950. Google Scholar15. SORGERTAYLOR KWA: Generalized sarcoidosis: report of a case terminating in fatal nephropathy. Arch. Path. (Chicago) 71: 35, 1961. Google Scholar16. BESSELIEBERMANLUSTED BEJELB: Kidney size in acute leukemia. Amer. J. Roentgen. 80: 611, 1958. Google Scholar17. TELIUM G: Glomerular lesions of kidneys in sarcoidosis. Acta Path. Microbiol. Scand. 28: 294, 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Montreal, Quebec,From the Department of Medicine and Pathology of the Montreal General Hospital, Montreal, P. Q., Canada, and from the Renal Service of the Departments of Medicine and Pathology, the Montreal General Hospital, Montreal, P. Q., Canada.Requests for reprints should be addressed to Richard I. Ogilvie, Associate Resident, Department of Pathology, University of Alberta, Edmonton, Alberta, Canada. 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