Why the study?
Do preoperative aspirin or warfarin increase mediastinal blood loss in patients undergoing coronary-artery bypass graft surgery?
Population
100 consecutive patients undergoing coronary-artery bypass graft surgery with normal preoperative hemostatic…
Comparison
Aspirin or warfarin sodium taken within 7 days… vs Control subjects not taking these agents within…
Design
Cohort
Follow-up
Postoperative period (until chest tube removal)
Authors
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May warrant considering recent aspirin or warfarin when assessing CABG bleeding risk; this cohort study leaves open causality and practice change.
Do preoperative aspirin or warfarin increase mediastinal blood loss in patients undergoing coronary-artery bypass graft surgery?
Preoperative use of aspirin or warfarin within 7 days of CABG surgery significantly increases postoperative mediastinal blood loss and prolongs the need for chest tube drainage.
Michael H. Torosian (1978) studied this question.
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