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April 1, 2002Antimicrobial Agents and ChemotherapyOpen Access

PCR-Restriction Fragment Length Polymorphism Can Also Detect Point Mutation A2142C in the 23S rRNA Gene, Associated with Helicobacter pylori Resistance to Clarithromycin

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Authors

AMArmelle MénardUniversité de BordeauxASAdriana SantosUniversidade Federal de Minas GeraisFMFrançis MégraudUniversity of Helsinki

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Ménard et al. (2002) studied this question.

synapsesocial.com/papers/6a814f35da9cafc35e339d80https://doi.org/10.1128/aac.46.4.1156-1157.2002
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Novel Method for Rapid Determination of Clarithromycin Sensitivity in Helicobacter pylori1999 · 77 citations
  2. 2Direct detection of Helicobacter pylori resistance to macrolides by a polymerase chain reaction/DNA enzyme immunoassay in gastric biopsy specimens1999 · 111 citations
  3. 3Accurate Prediction of Macrolide Resistance in Helicobacter pylori by a PCR Line Probe Assay for Detection of Mutations in the 23S rRNA Gene: Multicenter Validation Study2001 · 150 citations
  4. 4Rapid Detection, by PCR and Reverse Hybridization, of Mutations in the Helicobacter pylori 23S rRNA Gene, Associated with Macrolide Resistance1999 · 84 citations
  5. 5Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori1996 · 503 citations