Autonomic Dysfunction and Postural Orthostatic Tachycardia Syndrome Secondary to Abuse

Postural orthostatic tachycardia syndrome (POTS) and other forms of autonomic dysfunction are increasingly recognized in patients with histories of physical or psychological trauma. Emerging evidence suggests that trauma-related dysregulation of the autonomic nervous system may manifest as POTS, with hypervigilance and hyperadrenergic states proposed as potential mechanisms. However, the relationship between sexual abuse and subsequent autonomic dysfunction remains unclear. We present a series of patients referred to cardiology for suspected POTS, highlighting clinical features, potential mechanisms, and treatment considerations. These findings emphasize the need for trauma-informed evaluation to improve patient care and guide future research.