Why the study?
Do short half-life hypnotics (zaleplon or zolpidem) improve altitude tolerance and physical fitness in nonacclimated male soldiers compared to placebo?
Population
12 nonacclimated male soldiers undergoing military mountainous training at high altitude
Comparison
Zaleplon or zolpidem administered at 9:45 p.m… vs Placebo administered at 9:45 p.m. during 4 days…
Follow-up
3 periods of 4 days
Authors
Loading...
Hypothesis-generating link between nocturnal oxygenation and AMS; leaves open hypnotic benefits for soldier altitude tolerance pending RCTs.
Do short half-life hypnotics (zaleplon or zolpidem) improve altitude tolerance and physical fitness in nonacclimated male soldiers compared to placebo?
Short half-life hypnotics such as zolpidem or zaleplon may improve sleep and subsequent physical fitness during high-altitude military training.
Jouanin et al. (2009) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: