Why the study?
Outcomes and periinterventional differences between uninterrupted DOACs and VKA during AF ablation in real-world clinical practice remain controversial.
Does uninterrupted DOAC therapy improve efficiency and safety compared to VKA in patients undergoing AF-ablation?
Does uninterrupted DOAC therapy improve efficiency and safety compared to VKA in patients undergoing AF-ablation?
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Uninterrupted DOAC was associated with similar peri-procedural outcomes to VKA in AF ablation; hypothesis-generating for heparin dosing and requires prospective validation.
BACKGROUND: Uninterrupted direct oral anticoagulation (DOAC) in AF-ablation is recommended, proven by randomized trials. The outcome and the periinterventional differences between DOACs and VKA in the real world clinical practice are discussed controversial. HYPOTHESIS: To investigate efficiency and safety of uninterrupted DOAC therapy compared to VKA during AF-Ablation in real world setting with a focus on periinterventional heparin dosage.
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Christoph et al. (2021) studied this question.
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