We read with interest the study by Blessing et al¹assessing the value of fluorodeoxyglucose positron emission tomography and ultrasonography in detecting lymph node metastasis in patients with melanoma. The correct diagnosis of metastatic involvement of lymph nodes is a known challenge to the radiologist and clinician. Diagnosis of a lymph node metastasis using cross-sectional imaging modalities, ie, computed tomography and magnetic resonance imaging, is mainly based on size, choosing 1 to 1.5 cm as a cut-off value between benign and pathologic lymph nodes. However, using these criteria, micrometastases in small lymph nodes can be missed and reactively enlarged lymph nodes can cause false-positive results, limiting the value of the meth
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Roland Böni (1996) studied this question.