Key result
Single chamber ICD placement caused severe tricuspid regurgitation and right heart failure in a patient, requiring aquapheresis after diuretic failure.
Why the study?
Cardiac implantable electronic devices improve survival and cardiac synchrony, but can pose risks including lead-related tricuspid valve dysfunction and right heart failure.
Case Report (n=1)
Cardiac implantable electronic device leads can cause severe tricuspid regurgitation and right heart failure, which may require advanced therapies like aquapheresis if refractory to diuretics.
Supports vigilance for tricuspid regurgitation after ICD placement; hypothesis-generating for incidence and prevention in CIED recipients.
INTRODUCTION: Cardiac implantable electronic devices (CIEDs) have opened new doors, improving the quality, and increasing the duration of life by providing support of heart rate, atrioventricular and interventricular synchrony, thereby preventing sudden cardiac death. Nevertheless, these devices can pose some risks to the patients, including pacemaker-mediated cardiomyopathy and endocarditis. CASE PRESENTATION: We elucidate the case of a patient who had severe Tricuspid Regurgitation as a result of single chamber Implantable Cardioverter Defibrillator (ICD) placement which led to right heart failure (RHF). His chief complaints were generalized fatigability and difficulty climbing steps at home. He also had orthopnea but denies paroxysmal nocturnal dyspnea. Despite using home diuretic regimen (Torsemide 40 gm daily), his continued to increase. He did not respond well to intravenous diuretics that time so decision was made to start Aquapheresis to which he responded very well. DISCUSSION: TV dysfunction associated with CIED leads can be investigated and diagnosed using different techniques. These pillars of diagnostic tests include two-dimensional (2D), 3D, and Doppler echocardiography. Presence of holosystolic hepatic vein flow reversal is key in diagnosing severe TR, whereas normal antegrade systolic flow excludes the possibility of moderate and severe TR. CONCLUSION: CIED leads causing tricuspid valve impairment has become increasingly recognized over the recent times; however, the evidence underlying this trend has been derived primarily from retrospective analyses. In order to circumvent these issues, leadless pacemakers and subcutaneous ICD devices should be considered.
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Cheema et al. (2021) conducted a case report in Severe tricuspid regurgitation and right heart failure (n=1). Single chamber Implantable Cardioverter Defibrillator (ICD) placement was evaluated. Single chamber ICD placement caused severe tricuspid regurgitation and right heart failure in a patient, requiring aquapheresis after diuretic failure.
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