Key result
Age younger than 18 years (aOR 9.34), ASA physical status IV (aOR 9.83), and intraoperative blood loss of 2000-3000 ml (aOR 13.12) were significantly associated with an increased risk of delayed discharge from the anesthesia intensive care unit.
Why the study?
The study was designed to investigate the risk factors associated with delayed discharge from the Anesthesia Intensive Care Unit (AICU).
Cohort (n=14,338)
No
Delayed discharge from the anesthesia intensive care unit is significantly associated with extremes of age, high ASA physical status, abnormal BMI, preoperative complications, emergency surgery, and massive intraoperative blood loss.
Answers are grounded in this paper and cite their sources.
May inform risk stratification for delayed anesthesia ICU discharge; hypothesis-generating pending prospective validation.
BACKGROUND: A single-center retrospective study was designed to investigate the risk factors associated with delayed discharge from the Anesthesia Intensive Care Unit (AICU). METHODS: This retrospective study involved patients admitted in the AICU from January 2017 to December 2022. Risk factors for the delayed discharge from the AICU were analyzed by the binary multivariate logistic regression analysis. Nomogram was constructed to predict the risk of delayed discharge from AICU. The performance of the nomogram was assessed using the receiver operating characteristic curve and calibration curve. A decision curve analysis was also performed to determine the net benefit threshold of prediction. We utilized nomograms to visually express data analysis results. Based on receiver operating characteristic analysis, calibration plots, and decision curve analysis, we concluded that the nomogram model exhibited excellent performance. Patients undergoing spine surgeries suffered from the highest proportion of delayed discharge from the AICU, followed by those receiving orthopedic and vascular surgeries. Postoperative hemorrhage was the major cause of delayed discharge from an AICU, followed by septic shock, hypoperfusion and pulmonary insufficiency. CONCLUSION: The incidence of delayed discharge from the AICU in a single-center tertiary hospital is 1.54%. It is influenced by various risk factors, including age, ASA physical status classification, BMI, preoperative complications, type of surgery and intraoperative blood loss. The nomogram model exhibits excellent performance. TRIAL REGISTRATION: The single-center retrospective study was approved by the Ethics Committee of Nanjing Drum Tower Hospital (No. 2021-563-01, Data: 22 November 2021) and registered on the Chinese Clinical Trial Registry (No. ChiCTR2300078251, Data: 01 December 2023).
No takes yet. Share an insight, caveat, or question.
Hao et al. (2025) conducted a cohort in Postoperative patients requiring anesthesia intensive care (n=14,338). Age < 18 years vs. Age 18-64 years was evaluated on Delayed discharge from AICU (>24 hours) (aOR 9.34, 95% CI 5.24-16.01, p=<0.001). Age younger than 18 years (aOR 9.34), ASA physical status IV (aOR 9.83), and intraoperative blood loss of 2000-3000 ml (aOR 13.12) were significantly associated with an increased risk of delayed discharge from the anesthesia intensive care unit.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: