Fine needle aspiration biopsy of the mediastinum is generally accepted as a primary diagnostic modality for rapid confirmation of metastatic disease. It has also become a reliable procedure for the diagnosis of numerous primary mediastinal lesions. This review highlights the significant cytologic criteria for the diverse group of lesions encountered in mediastinal aspiration biopsy. Differential diagnoses and pitfalls are also discussed. As always, a solid foundation in surgical pathology and close communication with radiologists and clinicians will enhance diagnostic accuracy.
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Powers et al. (2001) studied this question.
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