Many patients who undergo operation for colo-rectal carcinoma have overt liver metastases, and treatment by means of intra-arterial radioisotope therapy in an attempt to eliminate clinical metastases was investigated. The efficacy of internal hepatic radionuclide therapy using $sup 32$P-radiocolloids with respect to reducing hepatic metastases gave good results when tested in rats. (CH)
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Grady et al. (1975) studied this question.