Key result
Anhedonia in patients with coronary artery disease was associated with significantly poorer health status and higher levels of somatic and cognitive symptoms both before and after cardiac rehabilitation.
Why the study?
Does anhedonia moderate the effectiveness of cardiac rehabilitation on health status and somatic and cognitive symptoms in patients with coronary artery disease?
Cohort (n=368)
No
Does anhedonia moderate the effectiveness of cardiac rehabilitation on health status and somatic and cognitive symptoms in patients with coronary artery disease?
Effect estimate: F(1,357) = 34.80
p-value: p=<0.001
Anhedonia is associated with poorer overall health status in CAD patients undergoing cardiac rehabilitation, though these patients may experience greater improvements in somatic and cognitive symptoms over time.
Anhedonia identifies CAD patients with poorer health status during rehabilitation; leaves open whether it moderates benefits or warrants targeted interventions.
PURPOSE: The effectiveness of cardiac rehabilitation (CR) in patients with coronary artery disease (CAD) is moderated by negative emotions and clinical factors, but no studies evaluated the role of positive emotions. This study examined whether anhedonia (i.e. the lack of positive affect) moderated the effectiveness of CR on health status and somatic and cognitive symptoms. METHODS: CAD patients (n = 368) filled out the Hospital Anxiety and Depression Scale (HADS) to assess anhedonia at the start of CR, and the Short-Form Health Survey (SF-36) and the Health Complaints Scale (HCS) at the start of CR and at 3 months to assess health status and somatic and cognitive symptoms, respectively. RESULTS: Adjusting for clinical and demographic factors, health status improved significantly during the follow-up (F(1,357) = 10.84, P = .001). Anhedonic patients reported poorer health status compared with non-anhedonic patients, with anhedonia exerting a stable effect over time (F(1,358) = 34.80, P < .001). Somatic and cognitive symptoms decreased over time (F(1,358) = 3.85, P = .05). Anhedonics experienced more benefits in terms of somatic and cognitive symptoms over time (F(1,358) = 13.00, P < .001). CONCLUSION: Anhedonic patients reported poorer health status and higher levels of somatic and cognitive symptoms prior to and after CR. Somatic and cognitive symptoms differed as a function of anhedonia over time, but health status did not. Anhedonia might provide a new avenue for secondary prevention in CAD.
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Pelle et al. (2010) conducted a cohort in Coronary artery disease (n=368). Anhedonia vs. Non-anhedonic patients was evaluated on Health status (SF-36) over time (F(1,357) = 34.80, p=<0.001). Anhedonia in patients with coronary artery disease was associated with significantly poorer health status and higher levels of somatic and cognitive symptoms both before and after cardiac rehabilitation.
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