Cells like sugar. General synthesis and potential of intracellular hydrophobic drug delivery of single-component polysaccharide capsules are pursued. The capsules can be generally assembled through hydrogen bonding networks but show striking shell robustness. The evidenced cell internalization, stimuli-responsiveness to local pH changes and high biocompatibilities of the capsules specifically favor their potential intracellular drug delivery.
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Wang et al. (2013) studied this question.
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