Physiologic Evaluation and Treatment of Kyphoscoliotic Patients

Article1 July 1961Physiologic Evaluation and Treatment of Kyphoscoliotic PatientsISRAEL BRUDERMAN, M.D., MYRON STEIN, M.D.ISRAEL BRUDERMAN, M.D.Search for more papers by this author, MYRON STEIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-1-94 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNew techniques of investigation have clarified the nature of the abnormalities of pulmonary function in patients with severe kyphoscoliosis. Restricted lung volumes, alveolar hypoventilation, hypercapnia, arterial oxygen unsaturation, and normal distribution of inspired air have been observed in these patients. However, arterial oxygen unsaturation when it occurs is unusually large for the degree of alveolar hypoventilation. Previous investigations have eliminated a diffusion abnormality (1) or atelectasis as a basis for this defect. The present study is concerned with the problem of arterial oxygen unsaturation and with the therapy of the acutely ill kyphoscoliotic patient.PATIENTS AND METHODSPATIENTSThree male...References1. BERGOFSKYTURINOFISHMAN EHGMAP: Cardiorespiratory failure in kyphoscoliosis. Medicine 38: 263, 1959. CrossrefMedlineGoogle Scholar2. COMROEFOWLER JHWS: Lung function studies. VI. Detection of uneven alveolar ventilation during a single breath of oxygen: a new test of pulmonary disease. Amer. J. Med. 10: 408, 1951. CrossrefMedlineGoogle Scholar3. COURNANDBALDWINDARLINGRICHARDS AEDRCDW Studies on the intrapulmonary mixing of gases. IV. The significance of the pulmonary emptying rate and a simplified open circuit measurement of residual air. J. Clin. Invest. 20: 681, 1941. CrossrefMedlineGoogle Scholar4. LILLYANDERSONHOWEY JCTFJP: The nitrogen meter. National Research Council. CMR-CAM Rep. No. 299, 1943. Google Scholar5. 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Author, Article, and Disclosure InformationAffiliations: Boston, MassachusettsReceived for publication March 4, 1961.From the Department of Medicine, Harvard Medical School, and the Medical Research Department of the Yamins Research Laboratories and the Medical Service, Beth Israel Hospital, Boston, Mass.Supported in part by U. S. Public Health Service Grant No. H-3795 (C2).Requests for reprints should be addressed to Myron Stein, M.D., Beth Israel Hospital, 330 Brookline Ave., Boston 15, Mass. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByRestrictive Lung DisordersControl of Breathing in Diseases of the Respiratory Tract and LungsSleep in Restrictive Lung DisordersAssisted ventilation at home: Is it worth considering?Arrest of alveolar multiplication in kyphoscoliosisUnexpected longevity in patients with severe kyphoscoliosis.Cuirass respirator treatment of chronic respiratory failure in scoliotic patients.Regional pulmonary ventilation and perfusion distribution in patients with untreated idiopathic scoliosisReversible pulmonary hypertension in a child with respiratory obstruction and cor pulmonale 1 July 1961Volume 55, Issue 1Page: 94-102KeywordsHospital medicineHypercapniaLungsMedical servicesNormal distributionOxygenPatientsPulmonary functionResearch laboratoriesRespiration Issue Published: 1 July 1961 PDF DownloadLoading ...