Hydrogenations of stigmasterol over 5% Pd/C, 5% Ru/C, Pt, Raney Ni, Raney Co, Ni/kieselguhr, and tris(triphenylphosphine)chlororhodium catalysts and with diimide generated from hydrazine and p ‐toluenesulfonylhydrazide were studied to determine the best conditons for the selective reduction of the Δ 22 double bond. The best results (maximum stigmasterol reduction, minimum stigmastanol formation) were obtained with Raney nickel at room temperature and atmospheric pressure.
No takes yet. Share an insight, caveat, or question.
Kircher et al. (1973) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: