Population
Isolated guinea-pig ventricular myocytes
Comparison
Application of adrenaline or extracellular ATP vs Control conditions without adrenaline or ATP
Design
Preclinical
Authors
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Adrenaline may slow pHi recovery in ventricular myocytes; leaves open in vivo effects on cardiac acid-base balance.
Adrenaline and extracellular ATP switch acid-equivalent extrusion in ventricular myocytes from a mechanism dependent on both HCO3- and H+ to one nearly exclusively dependent on H+.
Lagadic‐Gossmann et al. (1992) studied this question.
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