Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1β-cells in type II diabetes mellitus1991 · 586 citations
2. 2Establishment of a Pancreatic β Cell Line That Retains Glucose-Inducible Insulin Secretion: Special Reference to Expression of Glucose Transporter Isoforms*1990 · 1,287 citations
3. 3PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin1996 · 200 citations
4. 4Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters.1993 · 179 citations
5. 5Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.1993 · 214 citations