The disposition of morphine in serum and that in the cerebral cortex during normocarbia and hypercarbia were determined in dogs. Normocarbia (pHa‘ 7.41; PaCO2 36 torr) was maintained by controlled ventilation. Hypercarbia (pHa’ 7.41; PaCO2 69 torr) was induced by inhalation of 10 per cent CO2, balan
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Finck et al. (1977) studied this question.
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