Temporal trends and disparities in sudden cardiac death among colorectal cancer patients: A nationwide study

Figures

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  Figure 1. Crude death rate of SCD among CRC patients by sex and age group. Rates are presented per 100,000 population. Mortality increases progressively with age, with the highest burden observed among patients aged ≥85 years. Male patients consistently exhibit higher crude death rates compared to female patients across all age categories.

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  Figure 2. Age-adjusted death rate for sudden cardiac death (SCD) among colorectal cancer patients in the United States, 1999–2020. Rates are standardized to the 2000 U.S. standard population and expressed per 100,000 population. A significant linear decline is observed over the 21-year study period, decreasing from approximately 1.2 to 0.5 per 100,000, indicating a steady reduction in SCD-related mortality burden among colorectal cancer patients.

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  Figure 3. Age-adjusted death rates for sudden cardiac death (SCD) among colorectal cancer patients by sex in the United States, 1999–2020. Rates are expressed per 100,000 population and standardized to the 2000 U.S. standard population. Male patients consistently demonstrated higher mortality rates compared to females throughout the 21-year study period, although both groups experienced a general decline in mortality.

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  Figure 4. Age-adjusted death rates for sudden cardiac death (SCD) among colorectal cancer patients by race/ethnicity in the United States, 1999–2020. Rates are expressed per 100,000 population and standardized to the 2000 U.S. standard population. Although overall mortality declined across all racial groups during the study period, persistent disparities remained. Black or African American and Asian or Pacific Islander patients consistently had higher mortality rates compared to White patients. American Indian and Alaska Native patients demonstrated intermittent spikes, particularly in 2015, reflecting potential instability due to smaller population size but indicating a significant per-capita risk.

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  Figure 5. Crude death rates for sudden cardiac death (SCD) among colorectal cancer patients by United States, 1999–2020. Rates are expressed per 100,000 population. States such as Vermont, Nebraska, and Rhode Island show higher per-capita mortality burdens (darker shading), while larger states like California and Texas exhibit lower per-capita rates despite higher absolute case counts. States with insufficient data (e.g., Alaska) are shaded in gray.