A Rare Case of Multiple Myxoma Involving Both Mitral Valve Leaflets

Figures

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  Fig. 1. Echocardiography images. The diastolic period of both apical four-chamber view (A) and apical long axis views (C) showed two tumor masses (20 × 13 mm [red arrows] and 21 × 12 mm [blue arrow]) adherent to the anterior and posterior mitral valves. The loose-structured masses have a broad-based attachment with the mitral valves, and show large degree of mobility during the cardiac cycle and a certain degree of deformation. The masses are located in the left atrium during systole (B and D) and prolapsed into the left ventricle (A and C) through the mitral valve opening during diastole. Both apex four-chamber view (B) and the apical long axis view (D) during systole show a smaller substantive tumor (8 × 3 mm) at the left ventricular side of the root of the anterior mitral valve (yellow arrow). The blood flow velocity through the mitral valve during diastole is slightly faster (maximum flow velocity: 130 cm/s) (F). CDFI revealed a slight-to-moderate regurgitation signal at the mitral valve (E). LA: left atrium; LV: left ventricular; MV: mitral valve; CDFI: color Doppler flow imaging

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  Fig. 2. Histopathological examination of sections of lesions. The gross specimen (A) shows light brown, gray, and brown tissues, with a solid, soft, and translucent cross section (red arrows), which were attached to the mitral valve (blue arrow). The microscopic image (B) confirmed the masses to be myxomas (HE staining, × 100 magnification).