July 15, 2025International Journal of CardiologyOpen Access

Prevalence of hypertriglyceridemia and its association with extreme cardiovascular risk in patients with acute and chronic coronary syndrome enrolled in a cardiac rehabilitation program

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Why the study?

The prevalence of hypertriglyceridemia in patients with acute and chronic coronary syndrome in the current era of LDL-C targets remains unknown.

Is hypertriglyceridemia associated with extreme cardiovascular risk in patients with acute and chronic coronary syndrome?

Population

905 ACS/CCS patients participating in a cardiac rehabilitation program at Niguarda Hospital

Comparison

Triglyceride levels above 150 mg/dL vs normal triglyceride levels

Design

Observational cohort study

Authors

CTChiara TognolaAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda DBDavide Paolo BernasconiJohns Hopkins University RIRita Cristina Myriam IntravaiaOspedale Garibaldi

Discussion

Member takes

Implication

Hypertriglyceridemia may flag extreme CV risk in coronary syndrome patients; hypothesis-generating, prospective trials needed.

Structured PICO

Is hypertriglyceridemia associated with extreme cardiovascular risk in patients with acute and chronic coronary syndrome?

Population

905 patients with Acute and Chronic Coronary Syndrome (ACS and CCS) participating in a Cardiac Rehabilitation program at Niguarda Hospital (Milan) between January 1, 2012, and March 28, 2024.

Outcome

Prevalence of triglyceride (TG) levels ≥150 mg/dL and its association with extreme cardiovascular risk (defined as the occurrence of a CV event within two years or the presence of peripheral artery disease or multivessel coronary involvement)composite

In patients with coronary syndromes undergoing cardiac rehabilitation, elevated triglycerides remain prevalent despite LDL-C control and are strongly associated with extreme cardiovascular risk.

Cite This Study

Tognola et al. (2025) studied this question.

synapsesocial.com/papers/6a822efc81e5cfa450463173 https://doi.org/10.1016/j.ijcard.2025.133608

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Prevalence of hypertriglyceridemia and its association with extreme cardiovascular risk in patients with acute and chronic coronary syndrome enrolled in a cardiac rehabilitation program

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Prevalence of hypertriglyceridemia and its association with extreme cardiovascular risk in patients with acute and chronic coronary syndrome enrolled in a cardiac rehabilitation program

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider