A new process for the oxidation of 2-[(aryl)methyl]thio-1 H -imidazo[4,5- c ]pyridine to 2-[(aryl)methyl]sulfinyl-1 H -imidazo[4,5- c ]pyridine was achieved using NCS under mild condition. The reaction selectively affords the desired sulfoxide as the only product in high yield without further oxidation to the sulfone side product.
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Biao Jiang (1998) studied this question.
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