In Brief Evidence-based medicine (EBM) has evolved with at least three distinct components: the core evidence, the systematic methods of reviewing and synthesizing the evidence, and the use and application of the evidence in practice. This paper considers the tensions that exist because of different perceptions about the value, quality and interpretation of clinical and research evidence. The current challenges lie in developing better means of integrating different types of evidence from a range of sources to improve decisions about individual patients, and embedding guidelines in personal and stimulating clinical practice.
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Croft et al. (2011) studied this question.
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