The first edition of Joslin's book was his ownTreatment of Diabetes Mellitus: With Observations Upon the Disease Based Upon 1,000 Cases, published in 1916 (the cases now number more than 80,000). The penultimate version came out in 1959. The mass of new information that has emerged during the intervening 12 years has dictated that the present volume be substantially enlarged. Its title is appropriate, for it recognizes that much of the content is Joslin-inspired and reflects the principles and methods of that great physician and teacher. The four editors have been his intimates and pupils and most of the 26 contributors are or have been associated with the Joslin Clinic. Their ever-enthusiastic mentor would have been ecstatic about the timely appearance of the 11th edition during the 15th anniversary of the discovery of insulin. This is an exhaustive treatise. A number of chapters are monographs in themselves, as witness
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Henry T. Ricketts (1971) studied this question.