Why the study?
A dilated annulus is a risk factor for late failure of aortic valve repair if not addressed during surgery, but standardization using calibrated annuloplasty improves long-term outcomes.
Does aortic valve repair with calibrated annuloplasty reduce valve-related mortality and improve quality of life compared to prosthetic valve replacement in patients with dystrophic aortic insufficiency?
Does aortic valve repair with calibrated annuloplasty reduce valve-related mortality and improve quality of life compared to prosthetic valve replacement in patients with dystrophic aortic insufficiency?
Standardized aortic valve repair using calibrated annuloplasty addresses annular dilation, a key risk factor for late failure, and is associated with reduced mortality and improved quality of life compared to valve replacement.
Standardization of aortic valve repair techniques with use of a calibrated annuloplasty have led to improved long-term outcomes in dystrophic aortic insufficiency. It can also improve dissemination of techniques and rates of aortic valve repair. Dystrophic aortic insufficiency can be found in three aortic phenotypes: dilated aortic root, dilated ascending aorta and isolated aortic insufficiency. The aortic annulus is invariably dilated above 25 mm in the vast majority of cases of aortic insufficiency, regardless of whether the aorta is dilated or not. A dilated annulus is a risk factor for late failure of aortic valve repair if not addressed at the time of surgery. We perform a calibrated annuloplasty at both sub- and supra-valvular levels in order to restore the ratio of sinotubular junction and annulus. Current evidence shows aortic valve repair reduces valve-related mortality compared to prosthetic valve replacement, with an improved quality of life.
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Youssefi et al. (2021) studied this question.
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