The efficacy of liposome-encapsulated amphotericin B in the prophylaxis of disseminated Candida albicans infections in neutropenic mice was studied. The administration of liposome-encapsulated amphotericin B was associated with protection against infection with C. albicans when used at doses of greater than or equal to 2 mg of amphotericin B per kg of body weight. Neither empty liposomes nor free amphotericin B showed prophylactic efficacy.
No takes yet. Share an insight, caveat, or question.
Lopez‐Berestein et al. (1984) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: