Nanoscale Cancer Therapeutics: Advances, Hurdles and Hopes

Cancer constitutes many heterogeneous diseases having varied genetic and epigenetic abnormalities afflicting millions of people globally. Despite substantial progress in elucidating the complex molecular mechanisms underlying its cause, improvements in terms of therapeutic index have largely remained unchanged, while concomitant increases in the death rates have been steadily climbing over the past five decades. Failure to deliver effective treatment to cancer patients in the past has been the inability to get enough of the drug in the right amounts and form, and to the right place