Analysis of the Use of Various Antihypertensive Agents in Patients With Arterial Hypertension, Concomitant Type 2 Diabetes Mellitus and Obesity (Literature Review and Own Data)

Treatment of patients with arterial hypertension with diabetes and obesity requires taking into account the individual risk of complications and the use of appropriate differentiated tactics, and therefore the appointment of complex treatment with drugs that inhibit excessive activation of the renin-angiotensin-aldosterone system, in particular angiotensin converting enzyme inhibitors and angiotensin II receptor blockers, is the most appropriate and justified. Thus, a comparative analysis of the use of various treatment regimens in patients with arterial hypertension, concomitant type 2 diabetes mellitus and obesity was carried out using the angiotensinconverting enzyme inhibitor ramipril and the angiotensin II receptor blocker telmisartan. The inclusion of ramipril or telmisartan in standard therapy has been shown to have a positive effect on the structural and functional parameters of the left ventricle and ejection fractions. Also, at the same time, the neutral effect of these drugs on carbohydrate and improvement of some components of lipid metabolism in the examined category of patients was determined.