A review of the charts of 26 patients with squamous cell carcinoma of the nasal vestibule disclosed the following points: The disease occurs predominately in men 60 years old or older. Extension of the cancer into one or more of the areas of the base of the columella, the anterior floor of the nose, and the upper lip indicate an aggressive local growth and often is associated with regional lymph node metastasis. Surgery and radiation therapy are equally effective treatment for the primary lesion. Each of these modalities has advantages in individual cases. Three case reports illustrate some peculiarities of the disease and the potential for lymphatic metastasis.
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Goepfert et al. (1974) studied this question.