Isolated Growth Hormone Deficiency after Cerebral Edema Complicating Diabetic Ketoacidosis

CEREBRAL edema developing during the treatment of diabetic ketoacidosis is an uncommon but important cause of morbidity and mortality in children with diabetes mellitus.1 2 3 4 This report concerns a child who survived severe cerebral edema, which occurred during treatment for ketoacidosis, and subsequently had growth hormone deficiency. Although growth hormone deficiency has been described in long-standing diabetes, usually in association with other neuroendocrine abnormalities, we were unaware that it might occur after cerebral edema.Case ReportA girl four years and eight months old presented at a community hospital emergency room with classic symptoms of diabetic ketoacidosis. She was somnolent and . . .