Emerging evidence indicates that overexpression of a few âmaster regulatorsâ can dramatically alter cell type (transdifferentiation), in a process called direct reprogramming. The recent reprogramming of human fibroblasts into cardiomyocytes and endothelial cells augurs a new era in cardiovascular medicine by increasing the feasibility of cardiovascular regenerative therapy.
No takes yet. Share an insight, caveat, or question.
John P. Cooke (2013) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: