A Rh-catalyzed regioselective, stereoselective carbocyclization/borylation of acrylate-containing 1,6-enynes was described, which offers a general and practical method for constructing versatile and densely functionalized pyrrolidines with the ( Z ) geometry or the uncommon ( E ) geometry at the double bond with different substituents of the alkyne, with sterically hindered and conjugative aryl groups favoring the latter, featuring a tetrasubstituted vinyl boronate, containing an all-carbon quaternary stereocenter.
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Yang et al. (2023) studied this question.
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