Nickel(ii) Complexes With ‘Non Innocent’ Ligands – Cycloaminomethyl Derivatives of 1,2-Dihydroxybenzene: Sod-Like and Antimicrobial Activity

The process of Ni(II) ion complexation with cycloaminomethyl derivatives of 1,2-dihydroxybenzene in a water-ethanol medium was investigated. It was found potentiometrically that the complexes with the ratio M : L = 1 : 2 were formed in the solution, their overall stability constants were equal to 7,910 14 -1,610 15 . The Ni(II) complexes synthesized were shown to be amorphous, neutral, and thermally stable up to 150 C. Their coordination polyhedra have the composition [NiO2N2] and planar square geometry. It was shown that the Ni(II) complexes demonstrate a moderate or high level of antimicrobial activity against bacteria and fungi strains tested, as well as the ability to neutralize superoxide.