Septic Encephalopathy

Septic encephalopathy occurs easily in many septic persons. Manifestations are largely similar to those seen in other metabolic brain diseases. It can be detected most sensitivily, but not specifically, with electroencephalography. Diagnosis is based on excluding other causes of encephalopathy, such as a central nervous system infection or exposure to drugs or toxins. The pathogenesis is unknown but is likely diverse. Its severity correlates with mortality. Early recognition of septic encephalopathy is essential becuase early: diagnosis and treatment of sepsis markedly reduces mortality.