Why the study?
Does ketamine anaesthesia reduce early mortality compared to relaxant anaesthesia in elderly women undergoing operations for fractured neck of femur?
Does ketamine anaesthesia reduce early mortality compared to relaxant anaesthesia in elderly women undergoing operations for fractured neck of femur?
Ketamine anaesthesia reduces early mortality and thromboembolic complications compared to relaxant anaesthesia in elderly women undergoing fractured neck of femur surgery, though with worse surgical results.
Should not yet change practice for hip fracture anaesthesia; leaves open whether mortality benefit outweighs surgical risks in RCTs.
Ketamine has been compared with 'relaxant' anaesthesia in operations for fractured neck of femur in elderly women. Ketamine was found to reduce early mortality principally by a reduction in thromboembolic complications, but at the expense of more unsatisfactory surgical results. It is suggested that the mortality after relaxant anaesthesia for these operations is unacceptable.
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T.H. Spreadbury FFARCS (1980) studied this question.
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