Why the study?
The study was conducted to explore the prognostic value of ventricle epicardial fat volume calculated by CMR in patients with chronic heart failure.
Does ventricle epicardial fat volume (EFV) measured by CMR predict major adverse cardiovascular events in patients with chronic heart failure?
Does ventricle epicardial fat volume (EFV) measured by CMR predict major adverse cardiovascular events in patients with chronic heart failure?
Ventricle epicardial fat volume measured by CMR serves as a useful prognostic marker to identify patients with chronic heart failure at greater risk for major adverse cardiovascular events.
The purpose of this study is to explore the prognostic values of ventricle epicardial fat volume (EFV) calculated by cardiac magnetic resonance in patients with chronic heart failure (CHF). A total of 516 patients with CHF (left ventricular ejection fraction ≤ 50%) were recruited, and 136 (26.4%) of whom experienced major adverse cardiovascular events (MACE) within median follow-up of 24 months. The target marker-EFV was found to be associated with MACE in both univariate and multivariable analysis adjusted for various clinical variables (p < 0.01), regardless as a continuous variable and categorized by X-tile program. EFV also showed promising predictive ability, with an area under the curve of 0.612, 0.618, and 0.687 for the prediction of 1-year, 2-year, and 3-year MACE, respectively. In conclusion, EFV could be a useful prognostic marker for CHF patients, helping to identify individuals at greater risk of MACE.
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Cheang et al. (2023) studied this question.
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