Abstract 1‐Bromo‐3,5‐bis(trifluoromethyl)benzene ( 1 ) can be selectively prepared by treatment of 1,3‐bis(fluoromethyl)benzene with N,N' ‐dibromo‐5,5‐dimethylhydantoin in strongly acidic media. A number of synthetically useful reactions via 3,5‐bis(trifluoromethyl)phenylmagnesium, ‐lithium, and ‐copper intermediates were accomplished.
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Porwisiak et al. (1996) studied this question.
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