A new and efficient method for diazenylation reactions was developed with a Sc(OTf)3-catalyzed nitrogen-nitrogen bond cleavage process with triazenes. The transfer diazenylation reactions accommodate a diverse range of active methylene substrates including simple ketones to give aliphatic azo compounds that are of significant potential as azo prodrugs in high yields under mild conditions.
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Liu et al. (2014) studied this question.
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