Phthalimide‐N‐oxyl (PINO) Radical, a Powerful Catalytic Agent: Its Generation and Versatility Towards Various Organic Substrates

The last two decades represents a “start line” for the worldwide chemists, to develop new oxidizing methods, to replace the “old‐fashioned” ones, which are expensive, pollute the environment, and proceed in harsh conditions. One of the best candidates to satisfy the present global needs is N‐hydroxyphthalimide (NHPI), which can be used as a catalytic reagent successfully in a wide range of organic transformations. In this article, a review of the most frequently used methods to transform the NHPI into its nitroxyl radical correspondent, and the use of this powerful catalytic agent into various organic transformations, are presented.