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July 30, 2015PLoS ONEOpen Access

Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos

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Authors

ZHZhilian HuUniversity of OxfordJHJochen HolzschuhUniversity of FreiburgWDWolfgang DrieverUniversity of Freiburg

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Hu et al. (2015) studied this question.

synapsesocial.com/papers/6a828ec38757ed1e60133262https://doi.org/10.1371/journal.pone.0134299
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1DDB1 is essential for genomic stability in developing epidermis2007 · 61 citations
  2. 2Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 Forms a Nuclear E3 Ubiquitin Ligase with DDB1 and CUL4 That Is Involved in Multiple Plant Developmental Processes2008 · 167 citations