A series of new 2-aryl-7-fluoro-6-(4-methyl-1-piperazinyl)-4(3H)quinazolinones were prepared by the oxidative cyclization of the corresponding 2-arylidineamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzamides.The new quinazolinones were evaluated for their antitumor activity.
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Voelter et al. (2005) studied this question.
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