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The fluorescence of the probe 3,3'-dihexyl-2,2'-oxacarbocyanine (CC(6)) has been found to indicate potential across cell membranes. Results obtained in the present study using CC(6) and Drosophila mitochondria are in agreement with membrane potentials previously measured by Tupper and Tedeschi using microelectrodes. The results of both studies with Drosophila suggest that the potential across the mitochondrial membrane does not play a significant role in oxidative phosphorylation.
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Henry Tedeschi (1974) studied this question.
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