Population
Vascular smooth-muscle cells (VSMCs) from rat aortae
Design
Preclinical
Authors
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Stabilization of non-muscle MHC may be required for VSMC mitosis; leaves open relevance to human vascular proliferative disorders.
In rat vascular smooth muscle cells, non-muscle myosin heavy chain accumulates rapidly during the first M phase due to a significant decrease in its degradation rate, which may be necessary for cell division.
Grainger et al. (1991) studied this question.
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